NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE189820 Query DataSets for GSE189820
Status Public on Feb 10, 2023
Title Gene expression in duodenal biopsy samples from CVID enteropathy patients and healthy controls
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary A subgroup of CVID patients presents with gastrointestinal complications (enteropathy), which manifests in the duodenum as celiac like-diese ase. CVID enteropathy patients can present with severe histopathology in form of villous atrophy (CVID VA) or without VA (CVID noVA). RNAseq data from CVID VA and CVID noVA derived duodenal tissues were compared to each other and to healthy controls.
 
Overall design Duodenal biopsies derived from CVID patients and healthy controls during endoscopic procedures were dispersed using a homogenizer (T10, IKA) and total RNA was extracted using Rneasy Plus Mini Kit (Qiagen) according to manufacturer's instructions.
 
Contributor(s) Andrieux G, Boerries M, Strohmeier V, Unger S, Warnatz K
Citation(s) 36282455
Submission date Nov 29, 2021
Last update date Feb 10, 2023
Contact name Geoffroy Andrieux
Organization name University clinics Freiburg
Street address Breisacherstr 153
City Freiburg
ZIP/Postal code 79110
Country Germany
 
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (21)
GSM5708168 healthy control 1
GSM5708169 healthy control 5
GSM5708170 healthy control 6
Relations
BioProject PRJNA784599
SRA SRP348454

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE189820_count.txt.gz 1.2 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap