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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jun 15, 2024 |
| Title |
The role of RPA1 in T cells [spleen] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
As a single strand DNA binding protein, RPA1 participates in various cellular processes including DNA replication and DNA repair. However, the role of RPA1 in T cells is largely unknown. We generated a mouse model in which RPA1 was specifically deleted in T cells. Through single cell RNA sequencing, we reveal the immune landscape in RPA1 conditional knockout mice.
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| Overall design |
Study of immune cells in spleen from WT or RPA1 conditional knockout mice using 10x scRNA-seq technologies.
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| Contributor(s) |
Song J, Lu D, Zhang X |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Nov 23, 2021 |
| Last update date |
Jun 15, 2024 |
| Contact name |
Jia Song |
| E-mail(s) |
songjia@bjmu.edu.cn
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| Phone |
+18830053918
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| Organization name |
Peking University
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| Street address |
Peking University School of Medicine, 38 Xueyuan Road, Haidian District, Beijing
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| City |
Beijing |
| State/province |
China |
| ZIP/Postal code |
100080 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA783080 |
| SRA |
SRP347541 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE189467_RAW.tar |
191.4 Mb |
(http)(custom) |
TAR (of MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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