|
| Status |
Public on May 19, 2022 |
| Title |
TLR3 overexpression induces invasion of prostate cancer cells, whereas its activation triggers apoptosis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Toll-like receptors are proteins that play an important role in the innate immune system. They are frequently detected in immune cells such as macrophages or dendritic cells. Their role has been in part studied in prostate cancer. However, in the present study we focus mostly on their functional significance at various types of cancer therapy resistance.
|
| |
|
| Overall design |
Examination of differential gene expression analysis between control DU145 cells (clones A6, D7) and cells overexpressing TLR3 (clones B9, C12)
|
| |
|
| Contributor(s) |
Muresan XM, Procházková J, Hejret V, Souček K |
| Citation(s) |
35750257 |
| |
| Submission date |
Oct 15, 2021 |
| Last update date |
Aug 18, 2022 |
| Contact name |
Jirina Prochazkova |
| E-mail(s) |
prochazkova@ibp.cz
|
| Organization name |
Institute of Biophysics CAS
|
| Department |
Cytokinetics
|
| Lab |
Souceklab
|
| Street address |
Kralovopolska 135
|
| City |
Brno |
| ZIP/Postal code |
61265 |
| Country |
Czech Republic |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA771529 |
| SRA |
SRP341542 |
Less...
More...