NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE184064 Query DataSets for GSE184064
Status Public on Jan 19, 2022
Title Mitochondrial DNA base editing in vivo via viral DdCBE delivery to somatic cells
Organism Mus musculus
Experiment type Other
Summary We show that delivering the mitochondrial base editor DdCBEs via AAV transduction of somatic cells efficiently produces precise base editing of the intended region.
 
Overall design Base editing of cytosine to thymine of total DNA of mouse heart and cells.
 
Contributor(s) Van Haute L, Silva-Pinheiro P
Citation(s) 35136065
Submission date Sep 13, 2021
Last update date Apr 20, 2022
Contact name Lindsey Van Haute
Organization name University of Cambridge
Department MRC Mitochondrial Biology Unit
Street address Hills Road
City Cambridge
ZIP/Postal code CB2 0XY
Country United Kingdom
 
Platforms (1)
GPL16417 Illumina MiSeq (Mus musculus)
Samples (122)
GSM5577032 Vehicle, NIH/3T3_c
GSM5577033 Vehicle, NIH/3T3_c6
GSM5577034 Nd3-9577-(1), NIH/3T3_1
Relations
BioProject PRJNA762944
SRA SRP336894

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE184064_GSM5736820-GSM5736891_Supp_Dataset_1.xlsx 14.6 Kb (ftp)(http) XLSX
GSE184064_GSM5736820-GSM5736891_Supp_Dataset_2.xlsx 16.6 Kb (ftp)(http) XLSX
GSE184064_Supp_Dataset_1.xlsx 14.3 Kb (ftp)(http) XLSX
GSE184064_counts_ddCBE.xls.gz 166.2 Kb (ftp)(http) XLS
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record
| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap