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Series GSE181909 Query DataSets for GSE181909
Status Public on Jan 12, 2022
Title Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Our study reveals that while antiestrogen therapies effectively limit tumor growth in ER-positive breast cancers, they also trigger a transcriptional program that favors immune evasion.
Overall design Study of differential gene expression among wt and CSK k.o. MCF-7 breast cancer cells cultured in DMEM or Fulvestrant
Contributor(s) Hühn D, Marti-Rodrigo P, Mouron S, Hansel C, Tschapalda K, Porebski B, Häggblad M, Lidemalm L, Quintela-Fandino MA, Carreras-Puigvert J, Fernandez-Capetillo O
Citation(s) 34392603
Submission date Aug 11, 2021
Last update date Jan 12, 2022
Contact name Anastasios Erik Damdimopoulos
Organization name Karolinska Institute
Department Department of Biosciences and Nutrition
Lab Bioinformatics and Expression Analysis Core Facility
Street address Hälsovägen 7c
City Stockholm
State/province Huddinge
ZIP/Postal code 141 83
Country Sweden
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (18)
GSM5514185 MCF7 WT DMSO_Rep1
GSM5514186 MCF7 WT DMSO_Rep2
GSM5514187 MCF7 WT DMSO_Rep3
BioProject PRJNA753846
SRA SRP332109

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Supplementary file Size Download File type/resource
GSE181909_counts.txt.gz 5.5 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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