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Series GSE181386 Query DataSets for GSE181386
Status Public on Oct 05, 2021
Title Cumulative in-cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse Hoxd cluster [cHi-C]
Organism Mus musculus
Experiment type Other
Summary We used Capture Hi-C enriching the Hoxd locus and its flanking TADs to study the effects of CRISPR/Cas9-induced CTCF binding sites deletions on chromatin architecture. We analysed wildtype and homozygous mutant E9.5 trunks and E12.5 distal and proximal forelimbs.
 
Overall design We used Capture Hi-C enriching the Hoxd locus and its flanking TADs to study the effects of CRISPR/Cas9-induced CTCF binding sites deletions on chromatin architecture. We analysed wildtype and homozygous mutant E9.5 trunks and E12.5 distal and proximal forelimbs.
 
Contributor(s) Amândio AR, Beccari L, Lopez-Delisle L, Mascrez B, Zakany J, Gitto S, Duboule D
Citation(s) 34711654
Submission date Aug 03, 2021
Last update date Nov 18, 2021
Contact name Lucille Lopez-Delisle
E-mail(s) lucille.delisle@epfl.ch
Organization name EPFL
Street address Station 19
City Lausanne
ZIP/Postal code 1015
Country Switzerland
 
Platforms (2)
GPL19057 Illumina NextSeq 500 (Mus musculus)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (16)
GSM5501465 E9.5 trunk WT cHiC rep1
GSM5501466 E9.5 trunk WT cHiC rep2
GSM5501467 E9.5 trunk Del(CBS1) cHiC rep1
This SubSeries is part of SuperSeries:
GSE181387 Cumulative in-cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse Hoxd cluster
Relations
BioProject PRJNA751985
SRA SRP331020

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE181386_E9.5_trunk_DelCBS1-3_cHiC_merge_10kb.cool.gz 296.4 Kb (ftp)(http) COOL
GSE181386_E9.5_trunk_DelCBS1-5_cHiC_merge_10kb.cool.gz 298.4 Kb (ftp)(http) COOL
GSE181386_E9.5_trunk_DelCBS1_cHiC_merge_10kb.cool.gz 298.5 Kb (ftp)(http) COOL
GSE181386_E9.5_trunk_WT_cHiC_merge_10kb.cool.gz 294.8 Kb (ftp)(http) COOL
GSE181386_RAW.tar 485.8 Mb (http)(custom) TAR (of COOL, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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