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Status |
Public on Jul 30, 2021 |
Title |
Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on super-enhancers [RNA-seq] |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
RNA-seq analysis of Aire+/+ and Aire-/- mTECs with or without deletion of STAG2 (SA-2).
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Overall design |
CD45-Ly51loMHCIIhi mTECs were FACS sorted and low input RNA-seq was perfomed.
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Contributor(s) |
Mathis D, Benoist C |
Citation missing |
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Submission date |
Jul 27, 2021 |
Last update date |
Jul 30, 2021 |
Contact name |
CBDM Lab |
E-mail(s) |
cbdm@hms.harvard.edu
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Phone |
617-432-7747
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Organization name |
Harvard Medical School
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Department |
Microbiology and Immunobiology
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Lab |
CBDM
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Street address |
77 Avenue Louis Pasteur
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City |
Boston |
State/province |
MA |
ZIP/Postal code |
02215 |
Country |
USA |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (13)
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GSM5478663 |
Fonx1-cre(+/-).STAG2(fl/fl)_#1 [RNA-seq] |
GSM5478664 |
Fonx1-cre(+/-).STAG2(fl/fl)_#2 [RNA-seq] |
GSM5478665 |
Fonx1-cre(+/-).STAG2(fl/fl)_#3 [RNA-seq] |
GSM5478666 |
Fonx1-cre(+/-).STAG2(fl/fl)_#4 [RNA-seq] |
GSM5478667 |
STAG2(fl/fl).Aire(-/-)_#1 [RNA-seq] |
GSM5478668 |
STAG2(fl/fl).Aire(-/-)_#2 [RNA-seq] |
GSM5478669 |
STAG2(fl/fl).Aire(-/-)_#3 [RNA-seq] |
GSM5478670 |
Foxn1-cre(+/-).STAG2(fl/fl).Aire(-/-)_#1 [RNA-seq] |
GSM5478671 |
Foxn1-cre(+/-).STAG2(fl/fl).Aire(-/-)_#2 [RNA-seq] |
GSM5478672 |
Foxn1-cre(+/-).STAG2(fl/fl).Aire(-/-)_#3 [RNA-seq] |
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This SubSeries is part of SuperSeries: |
GSE180937 |
Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on super-enhancers |
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Relations |
BioProject |
PRJNA750246 |
SRA |
SRP330312 |