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Series GSE179307 Query DataSets for GSE179307
Status Public on Mar 01, 2022
Title Triple combination of BET plus pan-PI3K and NF-κB inhibitors exhibit synergistic activity in adult T cell leukemia/lymphoma
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We exploited the use of I-BET762, copanlisib, and bardoxolone methyl inhibitors as triple combination to understand the interactions between these three pathways in Adult T cell leukemia/lymphoma.
Overall design Examination of ATL43Tb (-) tumor isolated from NSG mice treated with either vehicle or Triple combination of I-BET762, Copanlisib and bardoxolone methyl.
Contributor(s) Daenthanasanmak A, Waldmann TA, Homan P
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Submission date Jul 01, 2021
Last update date Mar 01, 2022
Contact name Anusara Daenthanasanmak
Organization name National Institutes of Health
Department Lymphoid Malignancies Branch
Street address 10 Center Dr
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (8)
GSM5414109 Vehicle [Sample1]
GSM5414110 Vehicle [Sample2]
GSM5414111 Vehicle [Sample3]
BioProject PRJNA743091
SRA SRP326720

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE179307_RawCountFile_rsemgenes.txt.gz 830.2 Kb (ftp)(http) TXT
GSE179307_TreatedvsVehical_voom_deg.csv.gz 1.5 Mb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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