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Series GSE179307 Query DataSets for GSE179307
Status Public on Mar 01, 2022
Title Triple combination of BET plus pan-PI3K and NF-κB inhibitors exhibit synergistic activity in adult T cell leukemia/lymphoma
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We exploited the use of I-BET762, copanlisib, and bardoxolone methyl inhibitors as triple combination to understand the interactions between these three pathways in Adult T cell leukemia/lymphoma.
 
Overall design Examination of ATL43Tb (-) tumor isolated from NSG mice treated with either vehicle or Triple combination of I-BET762, Copanlisib and bardoxolone methyl.
 
Contributor(s) Daenthanasanmak A, Waldmann TA, Homan P
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Submission date Jul 01, 2021
Last update date Mar 01, 2022
Contact name Anusara Daenthanasanmak
E-mail(s) anusara.daenthanasanmak@nih.gov
Organization name National Institutes of Health
Department Lymphoid Malignancies Branch
Street address 10 Center Dr
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
 
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (8)
GSM5414109 Vehicle [Sample1]
GSM5414110 Vehicle [Sample2]
GSM5414111 Vehicle [Sample3]
Relations
BioProject PRJNA743091
SRA SRP326720

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE179307_RawCountFile_rsemgenes.txt.gz 830.2 Kb (ftp)(http) TXT
GSE179307_TreatedvsVehical_voom_deg.csv.gz 1.5 Mb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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