|
| Status |
Public on Jan 19, 2022 |
| Title |
Next-generation sequencing is useful for quantitative analysis of the transcriptome of RSL3@O2-ICG NBS combined with low-frequency ultrasound treated and untreated HCC cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Hepatocellular carcinoma has a hidden onset and is often found at an advanced stage clinically. Moreover, because it is insensitive to radiotherapy and chemotherapy, its treatment is often difficult. Therefore, we constructed a new type of ultrasound contrast agent RSL3@O2-ICG NBS, combined with low frequency ultrasound irradiation, to realize the integration of diagnosis and treatment of hepatocellular carcinoma. At the same time, next-generation high-throughput RNA sequencing (RNA-seq) was performed to accurately analyze the differential expression of mRNA and lncRNA targets after adding RSL3@O2-ICG NBS and using low-frequency ultrasound (LFU)
|
| |
|
| Overall design |
The transcripts of two kinds of HCC cells before and after RSL3@O2-ICG NBS combined with low-frequency ultrasound were detected
|
| |
|
| Contributor(s) |
Chen Y, Wu B, Shang H, Cheng W |
| Citation(s) |
35027829 |
| |
| Submission date |
Jun 21, 2021 |
| Last update date |
Jan 19, 2022 |
| Contact name |
Bolin Wu |
| Organization name |
Harbin Medical University Cancer Hospital
|
| Street address |
No.150, Haping Road, Nangang District
|
| City |
Harbin |
| State/province |
Heilongjiang Province |
| ZIP/Postal code |
150081 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA739675 |
| SRA |
SRP324856 |
Less...
More...