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Series GSE17477 Query DataSets for GSE17477
Status Public on Feb 28, 2010
Title Expresson from human THP-1 stimulated with IFN-g and/or infected with TB
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Investigation of interacting effects of TB and IFN-g on gene expression regulation within human macrophage-like THP-1 cells
Overall design To investigate the effect TB infection has on THP-1 macrophage’s response to IFN-g post-infection, in multiple experiments, THP-1 cells were exposed to each of the following four conditions: not treated, IFN-γ treated, M. tuberculosis infected and M. tuberculosis infected then IFN-γ treated. Total cellular RNA was then extracted. Recovered RNAs were pre-qualified for reproducibility by comparing qRT-PCR results of IFIT-2 and IP10 between replicate experiments. Four most reproducible replicate experiments were then selected for genome-wide mRNA abundance assays using Affymetrix microarray-based technology.
Contributor(s) Pine R
Citation(s) 23378427
Submission date Aug 03, 2009
Last update date Nov 24, 2019
Contact name Richard Pine
Phone 973-854-3320
Organization name UMDNJ-NJMS
Department PHRI/Medicine
Street address 225 Warren St
City Newark
State/province NJ
ZIP/Postal code 07103
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (16)
GSM435893 THP1, IFN-g treated, biological rep 1
GSM435894 THP1, IFN-g treated, biological rep 2
GSM435895 THP1, IFN-g treated, biological rep 3
BioProject PRJNA118703

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17477_RAW.tar 52.4 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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