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Series GSE17409 Query DataSets for GSE17409
Status Public on Jan 10, 2010
Title Pregnancy changes expression in peripheral blood mononuclear cells of healthy donors
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Background: pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood.
This data series contains the subset of data used to generate a healthy donors signature comparing female healthy specimens before pregnancy with respect to female healthy specimens at ninth month pregnancy.
Overall design Subjects were followed in the outpatients clinic and blood was collected before pregnancy and at the following time points during pregnancy: first trimester (gestational age at sampling 12 weeks), second trimester (24 weeks), and third trimester (36 weeks). Before-pregnancy samples were obtained in a treatment-free period and after anticonceptional drug withdrawal.
Peripheral blood mononuclear cells (PBMCs) obtained from 11 women (7 healthy donors before pregnancy and 4 healthy donors at 9th month pregnancy) were analyzed by oligonucleotide microarray technology.
Contributor(s) Gilli F, Lindberg R, Valentino P, Marnetto F, Malucchi S, Sala A, Capobianco M, di Sapio A, Sperli F, Kappos L, Calogero RA, Bertolotto A
Citation(s) 20126412
Submission date Jul 30, 2009
Last update date Dec 06, 2018
Contact name Raffaele A Calogero
Phone ++39 0116706454
Organization name University of Torino
Department Molecular Biotechnology Center
Lab Bioinformatics and Genomics Unit
Street address Via Nizza 52
City Torino
State/province To
ZIP/Postal code 10126
Country Italy
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (11)
GSM434510 MDL1 preN
GSM434512 VC1 preN
GSM434518 21 preN
This SubSeries is part of SuperSeries:
GSE17449 Transcription signature of Multiple Sclerosis
BioProject PRJNA123613

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17409_RAW.tar 20.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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