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Series GSE17393 Query DataSets for GSE17393
Status Public on Jan 10, 2010
Title Transcription signature of Multiple Sclerosis in peripheral blood mononuclear cells.
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Background: pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood.
This data series contains the subset of data used to generate a MS signature comparing female healthy specimens with respect to MS patients
Overall design Subjects were followed in the outpatients clinic and blood was collected before pregnancy and at the following time points during pregnancy: first trimester (gestational age at sampling 12 weeks), second trimester (24 weeks), and third trimester (36 weeks). Before-pregnancy samples were obtained in a treatment-free period and after anticonceptional drug withdrawal.
Peripheral blood mononuclear cells (PBMCs) obtained from 15 women (8 MS patients and 7 healthy controls) were analyzed by oligonucleotide microarray technology.
Contributor(s) Gilli F, Lindberg R, Valentino P, Marnetto F, Malucchi S, Sala A, Capobianco M, di Sapio A, Sperli F, Kappos L, Calogero R, Bertolotto A
Citation(s) 20126412
Submission date Jul 29, 2009
Last update date Dec 06, 2018
Contact name Raffaele A Calogero
Phone ++39 0116706454
Organization name University of Torino
Department Molecular Biotechnology Center
Lab Bioinformatics and Genomics Unit
Street address Via Nizza 52
City Torino
State/province To
ZIP/Postal code 10126
Country Italy
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (15)
GSM434504 DD1 preMS
GSM434505 RP1 preMS
GSM434506 SDC1 preMS
This SubSeries is part of SuperSeries:
GSE17449 Transcription signature of Multiple Sclerosis
BioProject PRJNA123611

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17393_RAW.tar 27.4 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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