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Series GSE172405 Query DataSets for GSE172405
Status Public on Nov 22, 2022
Title p63/p73 maintain cancer stem cells in a quasi-mesenchymal state and drive metastatic colonization via EGFR signaling [ATAC-Seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary p63/p73 are master transcriptional regulators of ITGB4-hi cancer stem cells and are required to maintain CSCs in a quasi-mesenchymal state and for metastatic colonization
 
Overall design ATAC-seq of SUM159 ITGB4-hi or SUM159 ITGB4-low cells.
 
Contributor(s) Lambert A, Fiore C, Wollison B, Guenther M, Weinberg R
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Apr 20, 2021
Last update date Nov 23, 2022
Contact name Matt Guenther
Organization name Syros Pharmaceuticals
Street address 35 Cambridge Park Dr 4th floor
City Cambridge
State/province MA
ZIP/Postal code 02140
Country USA
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (4)
GSM5255084 MWC88.ATAC SUM159 CD104-low Rep1
GSM5255085 MWC89.ATAC SUM159 CD104-low Rep2
GSM5255086 MWC90.ATAC SUM159 CD104-high Rep1
This SubSeries is part of SuperSeries:
GSE172407 p63/p73 maintain cancer stem cells in a quasi-mesenchymal state and drive metastatic colonization via EGFR signaling
Relations
BioProject PRJNA723261
SRA SRP315528

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE172405_RAW.tar 1.3 Gb (http)(custom) TAR (of BED, BIGWIG, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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