|
Status |
Public on Nov 03, 2021 |
Title |
Maladaptive functional changes in alveolar fibroblasts due to perinatal hyperoxia impair epithelial differentiation |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
PDGFRa+ matrix and myofibroblasts decrease and PDGFRa+ lipofibroblasts increase during hyperoxia injury at both a transcriptional and population level.
|
|
|
Overall design |
MACS-sorted PDGFRa+ (CD140+) FBs from either RA or O2 PN4, PN7, and PN10 mouse lungs were prepared for bulk RNA-seq.
|
|
|
Contributor(s) |
Riccetti M, Snowball J, Per AT |
Citation(s) |
35113810 |
|
Submission date |
Apr 09, 2021 |
Last update date |
Jun 10, 2022 |
Contact name |
John M. Snowball |
E-mail(s) |
snowballdbs@yahoo.com
|
Phone |
8594090321
|
Organization name |
Cincinnati Childrens Hospital
|
Department |
Pulmonary Research
|
Lab |
Whitsett
|
Street address |
3333 Burnet Ave
|
City |
Cincinnati |
State/province |
OH |
ZIP/Postal code |
45229 |
Country |
USA |
|
|
Platforms (1) |
GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
Samples (18)
|
|
Relations |
BioProject |
PRJNA720949 |
SRA |
SRP314252 |