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Status |
Public on Apr 02, 2024 |
Title |
Genome-wide maps of chromatin state in MDA-MB-231 cells |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
In order to figure out the genomic binding landscape of CARM1, we analyzed the genome-wide transcriptional targets for CARM1 using the Chromatin immunoprecipitation based-deep sequencing (ChIP-seq) in MDA-MB-231 cells with antibodies against CARM1. Using Illumina instrument, we found lots of CARM1-specific binding peaks and strong enrichment on the promoters of selected genes involved in classical pathways. This study gave us a new understanding of the role of CARM1 in chromatin status and gene transcription.
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Overall design |
Examination of CARM1 target genes in MDA-MB-231 cell line
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Contributor(s) |
Feng D, Wang Y |
Citation missing |
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Submission date |
Apr 09, 2021 |
Last update date |
Apr 02, 2024 |
Contact name |
yan wang |
E-mail(s) |
yanwang@tmu.edu.cn
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Organization name |
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences
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Street address |
17 panjiayuan nanli, chaoyang district, Beijing, China
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City |
beijing |
ZIP/Postal code |
100021 |
Country |
Zimbabwe |
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Platforms (1) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (2) |
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Relations |
BioProject |
PRJNA720844 |
SRA |
SRP314194 |