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Series GSE171767 Query DataSets for GSE171767
Status Public on Apr 02, 2024
Title Genome-wide maps of chromatin state in MDA-MB-231 cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary In order to figure out the genomic binding landscape of CARM1, we analyzed the genome-wide transcriptional targets for CARM1 using the Chromatin immunoprecipitation based-deep sequencing (ChIP-seq) in MDA-MB-231 cells with antibodies against CARM1. Using Illumina instrument, we found lots of CARM1-specific binding peaks and strong enrichment on the promoters of selected genes involved in classical pathways. This study gave us a new understanding of the role of CARM1 in chromatin status and gene transcription.
 
Overall design Examination of CARM1 target genes in MDA-MB-231 cell line
 
Contributor(s) Feng D, Wang Y
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Apr 09, 2021
Last update date Apr 02, 2024
Contact name yan wang
E-mail(s) yanwang@tmu.edu.cn
Organization name National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences
Street address 17 panjiayuan nanli, chaoyang district, Beijing, China
City beijing
ZIP/Postal code 100021
Country Zimbabwe
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (2)
GSM5233642 Input DNA
GSM5233643 CARM1-ChIPseq
Relations
BioProject PRJNA720844
SRA SRP314194

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE171767_RAW.tar 1.1 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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