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| Status |
Public on Nov 04, 2021 |
| Title |
Transcriptomics of Kidney Transplant Recipients after Cytomegalovirus DNAemia |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To study the gene expression dynamics in cytomegalovirus (CMV) DNAemic patients after kidney transplantation, we performed RNA sequencing (RNAseq) on 31 DNAemic patients at 4 timepoints (baseline, 1 week post-DNAemia, 1 month post-DNAemia, and a long-term timepoint 9-18 months post-DNAemia) matched with 31 non-DNAemic patients at 2 timepoints (baseline and long-term).
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| Overall design |
Whole blood samples were obtained from kidney transplant patients that a) developed CMV DNAemia or b) did not develop CMV DNAemia. Baseline, 1 week post-DNAemia, 1 month post-DNAemia, and 9-18 months post transplant samples were collected from CMV DNAemic patients. Baseline and 9-18 months post transplant samples were collected from non-DNAemic patients. All samples were sequenced on the Illumina HiSeq3000 platform.
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| Contributor(s) |
Ahn R |
| Citation(s) |
34867983, 34609965 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| U19 AI128913 |
Mapping Immune Responses to CMV in Renal Transplant Recipients |
UNIVERSITY OF CALIFORNIA LOS ANGELES |
ELAINE F REED |
| U19 AI128913 |
Mapping Immune Responses to CMV in Renal Transplant Recipients |
UNIVERSITY OF CALIFORNIA LOS ANGELES |
Minnie M Sarwal |
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| Submission date |
Mar 09, 2021 |
| Last update date |
Jan 07, 2022 |
| Contact name |
Richard Sungho Ahn |
| Organization name |
University of California Los Angeles
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| Department |
Microbiology, Immunology, and Molecular Genetics
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| Street address |
611 Charles E. Young Drive East, UCLA, Boyer Hall, 510C
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| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90095 |
| Country |
USA |
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| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
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| Samples (154)
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| Relations |
| BioProject |
PRJNA708352 |
| SRA |
SRP310016 |
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