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Status |
Public on Aug 10, 2021 |
Title |
Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath [Cut&Tag] |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
Here, we describe CRISPRpath, a CRISPR screening strategy for simultaneously characterizing CREs in multiple genomic loci by leveraging converging phenotypes resulted from transcriptional defects in genes linked to the same biological pathway.
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Overall design |
Examination of histone modification (H3K4me3) and transcription factor binding (CTCF) in WTC11 human iPSCs.
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Contributor(s) |
Ren X, Shen Y |
Citation(s) |
34524848 |
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Submission date |
Feb 16, 2021 |
Last update date |
Sep 29, 2021 |
Contact name |
Yin Shen |
E-mail(s) |
Yin.Shen@ucsf.edu
|
Phone |
4155023403
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Organization name |
UCSF
|
Department |
Department of Neurology
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Lab |
Shen Lab
|
Street address |
513 Parnassus Ave
|
City |
SAN FRANCISCO |
State/province |
CALIFORNIA |
ZIP/Postal code |
94143-0410 |
Country |
USA |
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Platforms (2) |
GPL22790 |
Illumina MiniSeq (Homo sapiens) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (4)
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This SubSeries is part of SuperSeries: |
GSE166839 |
Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath |
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Relations |
BioProject |
PRJNA702103 |
SRA |
SRP306649 |