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Series GSE166836 Query DataSets for GSE166836
Status Public on Aug 10, 2021
Title Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath [Cut&Tag]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Here, we describe CRISPRpath, a CRISPR screening strategy for simultaneously characterizing CREs in multiple genomic loci by leveraging converging phenotypes resulted from transcriptional defects in genes linked to the same biological pathway.
 
Overall design Examination of histone modification (H3K4me3) and transcription factor binding (CTCF) in WTC11 human iPSCs.
 
Contributor(s) Ren X, Shen Y
Citation(s) 34524848
Submission date Feb 16, 2021
Last update date Sep 29, 2021
Contact name Yin Shen
E-mail(s) Yin.Shen@ucsf.edu
Phone 4155023403
Organization name UCSF
Department Department of Neurology
Lab Shen Lab
Street address 513 Parnassus Ave
City SAN FRANCISCO
State/province CALIFORNIA
ZIP/Postal code 94143-0410
Country USA
 
Platforms (2)
GPL22790 Illumina MiniSeq (Homo sapiens)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (4)
GSM5086287 Cut&Tag_WTC11 iPSCs - H3K4me3_rep1
GSM5086288 Cut&Tag_WTC11 iPSCs - H3K4me3_rep2
GSM5086289 Cut&Tag_WTC11 iPSCs - CTCF_rep1
This SubSeries is part of SuperSeries:
GSE166839 Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath
Relations
BioProject PRJNA702103
SRA SRP306649

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE166836_CTCF.bw 120.9 Mb (ftp)(http) BW
GSE166836_CTCF_peaks.bed.gz 587.8 Kb (ftp)(http) BED
GSE166836_H3K4me3.bw 82.1 Mb (ftp)(http) BW
GSE166836_H3K4me3_peaks.bed.gz 619.8 Kb (ftp)(http) BED
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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