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Status |
Public on Jan 11, 2022 |
Title |
Hepatic Interferon Regulatory Factor 3 Fuels Gluconeogenesis via PP2A-mediated Inactivation of AMP Kinase |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
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Summary |
We report the IRF3 transcriptome and cistrome in primary mouse hepatocytes.
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Overall design |
RNA-seq and IRF3 CUT&RUN was performed in primary mouse hepatocytes expressing constitutively active IRF3 (IRF3-2D) and control mCherry.
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Contributor(s) |
Patel SJ, Rosen ED |
Citation(s) |
35320000 |
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Submission date |
Feb 08, 2021 |
Last update date |
Jun 21, 2022 |
Contact name |
NORC Boston |
E-mail(s) |
fungen.core@gmail.com
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Organization name |
Beth Israel Deaconess Medical Center
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Street address |
3 Blackfan Circle, CLS0733
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City |
Boston |
State/province |
MA |
ZIP/Postal code |
02115 |
Country |
USA |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (10)
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Relations |
BioProject |
PRJNA700631 |
SRA |
SRP305333 |