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Series GSE164899 Query DataSets for GSE164899
Status Public on Mar 31, 2022
Title Gene expression profiles of ears infected with Staphylococcus aureus at ZT4
Organism Mus musculus
Experiment type Expression profiling by array
Summary We analysed the gene expression profiles after infection of Staphylococcus aureus at ZT4 in CXCL14-KO mice. The group of genes categolized as GO defense response (GO: 006952) were upregulated upon a response to Staphylococcus aureus infection.
The expression of IL1b, Cxcl2, and Ccl3 were significantly suppressed in infected ear of Cxcl14-KO compared to that of WT.
Overall design PBS with or without 10^7 CFUs of S. aureus were injected intradermally into the pinnae of each ear of WT-C57BL/6 or Cxcl14-KO mice using a 30G insulin syringe at ZT4. Their ears were subjected to microarray andlysis after 3 hours post injection.
Contributor(s) Tanegashima K, Tsujihana K, Nishito Y, Okamura H, Hara T
Citation(s) 35704759
Submission date Jan 15, 2021
Last update date Jun 30, 2022
Contact name Kosuke Tanegashima
Phone +81-3-5316-3130
Organization name Tokyo Metropolitan Institute of Medical Science
Lab Stem cell project
Street address 2-1-6 Kamikitazawa
City Setagaya-ku
State/province Tokyo
ZIP/Postal code 156-8506
Country Japan
Platforms (1)
GPL10333 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Feature Number version)
Samples (4)
GSM5022607 Ear WT, 3hr, PBS
GSM5022608 Ear WT, 3hr, S.aureus
GSM5022609 Ear KO, 3hr, PBS
BioProject PRJNA692422

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE164899_RAW.tar 42.1 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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