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Status |
Public on Dec 23, 2023 |
Title |
The epigenetic effects induced by ectopic expression of Pax7 in 3T3-L1 |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing Expression profiling by high throughput sequencing
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Summary |
We report the robustness and plasticity of the differentiation potential of 3T3L1 adipocytes in the aspect of genome-wide change of chromatin structure by ectopic expression of Pax7 and classifying the genes potentially responsible for facilitating or suppressing trans-differentiation of 3T3L1 in the aspect of epigenetic regulation..
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Overall design |
We performed RNA-seq and ChIP-seq in control or Pax7 stably expressed 3T3-L1 adipocytes during adipocyte differentiation.
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Contributor(s) |
Elgaabari A, Miyawaki-Kuwakado A, Tomimatsu K, Wu Q, Izumi W, Suzuki T, Tokunaga K, Anderson JE, Tatsumi R, Ohkawa Y, Nakamura M |
Citation missing |
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Submission date |
Dec 23, 2020 |
Last update date |
Dec 23, 2023 |
Contact name |
Yasuyuki Ohkawa |
E-mail(s) |
yohkawa@bioreg.kyushu-u.ac.jp
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Organization name |
Medical Institute of Bioregulation
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Lab |
Division of Transcriptomics
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Street address |
3-1-1 Maidashi
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City |
Fukuoka |
ZIP/Postal code |
8128582 |
Country |
Japan |
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Platforms (2) |
GPL18480 |
Illumina HiSeq 1500 (Mus musculus) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (28)
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Relations |
BioProject |
PRJNA687599 |
SRA |
SRP299186 |