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| Status |
Public on May 16, 2022 |
| Title |
Leptin receptor marks and targets the hair follicle mesenchymal niche |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We report the single-cell transcriptomes of whole, unsorted backskin skin cells isolated from P46 Lepr-Cre;mTmG;Smo and Lepr-Cre;mTmG;Smo+/- female mice and sorted Lepr-expressing, GFP-positive cells isolated from backskin of P50 Lepr-Cre;mTmG female mice
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| Overall design |
Examination and comparison of gene expression and cell-cell signaling of whole, unsorted dorsal skin cells from P46 Lepr-Cre;mTmG;Smo and Lepr-Cre;mTmG;Smo+/- female mice; and examination of gene expression of sorted Lepr-expressing, GFP-positive cells from backskin of P50 Lepr-Cre;mTmG female mice.
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| Contributor(s) |
Liu Y, Guerrero-Juarez CF, Plikus MV, Nie Q |
| Citation(s) |
35777353 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 AR079150 |
Tissue Size and Precision Control in Growing Hair Follicles |
The Regents of the University of California |
Maksim V Plikus |
| R21 AR078939 |
Blastema-independent Mechanism for Regeneration in Salamanders |
The Regents of the University of California |
Maksim V Plikus |
| U01 AR073159 |
Multiscale Models of Wound Cell Plasticity for Regeneration |
The Regents of the University of California |
Maksim V Plikus |
|
| |
| Submission date |
Oct 30, 2020 |
| Last update date |
Feb 05, 2024 |
| Contact name |
Maksim V Plikus |
| E-mail(s) |
plikus@uci.edu
|
| Phone |
949-824-1260
|
| Organization name |
University of California, Irvine
|
| Department |
Developmental and Cell Biology
|
| Street address |
845 Health Sciences Road
|
| City |
Irvine |
| State/province |
California |
| ZIP/Postal code |
92697 |
| Country |
USA |
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| Platforms (2) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (5)
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| Relations |
| BioProject |
PRJNA673418 |
| SRA |
SRP290165 |
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