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Series GSE15730 Query DataSets for GSE15730
Status Public on Jan 04, 2010
Title Affymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Nsp SNP Array
Organism Homo sapiens
Experiment type SNP genotyping by SNP array
Genome variation profiling by SNP array
Summary Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML.
This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted from cryopreserved diagnostic bone marrow or peripheral blood samples.
Overall design 111 pediatric AML samples were studied using either Affymetrix 100K + 500K 5.0 SNP arrays, 65 of the samples had paired germ line material.

The supplemental files 'GSE15730_AML_175_SNP_Nsp_signal.txt' and 'GSE15730_AML_176_SNP_Nsp_signal.txt' contain the raw signals generated by dChip without normalization.

The CNA and LOH data can be found in the Supplemental Information of the associated manuscript.
Contributor(s) Radtke I, Downing JR
Citation(s) 19651601
Submission date Apr 17, 2009
Last update date May 17, 2017
Contact name Guangchun Song
Phone 901-595-5722
Organization name St Jude Children's Research Hospital
Department Pathology
Lab Klco
Street address 262 Danny Thomas Place
City Memphis
State/province TN
ZIP/Postal code 38105
Country USA
Platforms (1)
GPL3718 [Mapping250K_Nsp] Affymetrix Mapping 250K Nsp SNP Array
Samples (176)
GSM393572 Diagnostic_acute_leukemia AE-#1, Nsp SNP array
GSM393573 Germline AE-#1, Nsp SNP array
GSM393574 Diagnostic_acute_leukemia AE-#2, Nsp SNP array
This SubSeries is part of SuperSeries:
GSE15347 Analysis of pediatric acute myeloid leukemia (AML) samples at diagnosis
BioProject PRJNA123003

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE15730_AML_175_SNP_Nsp_signal.txt.gz 151.7 Mb (ftp)(http) TXT
GSE15730_AML_176_SNP_Nsp_signal.txt.gz 152.6 Mb (ftp)(http) TXT
GSE15730_RAW.tar 4.2 Gb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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