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Series GSE155984 Query DataSets for GSE155984
Status Public on Jan 04, 2021
Title Tissue specific transcription patterns support the kinship theory of intragenomic conflict in honey bees (Apis mellifera)
Organism Apis mellifera
Experiment type Expression profiling by high throughput sequencing
Summary Kin selection may act differently on genes inherited from the two parents (matrigenes and patrigenes), resulting in intragenomic conflict. This conflict can be observed as differential expression of matrigenes and patrigenes, or parent specific gene expression (PSGE). In honey bees (Apis mellifera), intragenomic conflict is hypothesized to occur in multiple social contexts. Previously, we found patrigene expression in reproductive tissues was associated with increased reproductive potential in worker honey bees, consistent with the prediction that patrigenes are selected to promote selfish behavior in this context. Here, we examined brain expression patterns to determine if PSGE is also found in other tissues. As before, the number of transcripts showing patrigene expression bias was significantly greater in the brains of reproductive versus sterile workers, while the number of matrigene-biased transcripts was not significantly different. Twelve transcripts out of the 374 showing PSGE in either tissue showed PSGE in both brain and reproductive tissues; this overlap was significantly greater than expected by chance. However, the majority of transcripts showed PSGE only in one tissue, suggesting the epigenetic mechanisms mediating PSGE show plasticity between tissues. There was no significant overlap between transcripts that showed PSGE and transcripts that were significantly differentially expressed. Weighted gene correlation network analysis identified modules which were significantly enriched in both types of transcripts, suggesting that these genes may influence each other through gene networks. Our results provide further support for the kin selection theory of intragenomic conflict, and provide valuable insights into the mechanisms which may mediate this process.
 
Overall design Examination of allele specific expression in the brains of reproductive and sterile honey bees. The samples were run across two lanes using paired end sequencing.
 
Contributor(s) Galbraith DA, Ma R, Grozinger CM
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Submission date Aug 10, 2020
Last update date Jan 04, 2021
Contact name David Asher Galbraith
E-mail(s) dag5031@gmail.com
Organization name Penn State University
Street address 19a Chemical Ecology Lab
City University Park
State/province Pennsylvania
ZIP/Postal code 16802
Country USA
 
Platforms (1)
GPL19174 Illumina HiSeq 2500 (Apis mellifera)
Samples (24)
GSM4718553 DG-S1_S10
GSM4718554 DG-S2_S11
GSM4718555 DG-S3_S12
Relations
BioProject PRJNA656275
SRA SRP276926

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE155984_PSGE_Reproductive_reads.txt.gz 135.3 Kb (ftp)(http) TXT
GSE155984_PSGE_Sterile_reads.txt.gz 133.7 Kb (ftp)(http) TXT
GSE155984_PSGE_gene_expression.txt.gz 608.0 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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