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Series GSE153738 Query DataSets for GSE153738
Status Public on Dec 10, 2020
Title Gene expression differences among human natural killer cells and recombinant expression hosts
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary This study was designed to identify gene expression differences in activatable cells used to test therapeutic monoclonal antibody efficacy in vitro. We characterized the types of glycans attached to CD16a that were expressed by four cell types and compared these compositional differences to gene expression.
 
Overall design At least three biological replicates of each cell type were performed. RNA was recovered from the primary human NK cells of three donors, and RNA was recovered from NK92, YTS and HEK293F cells grown in culture and analyzed by RNA-Seq.
 
Contributor(s) Barb AW
Citation(s) 33310702
Submission date Jul 02, 2020
Last update date Mar 11, 2021
Contact name Adam W. Barb
E-mail(s) abarb@uga.edu
Organization name University of Georgia
Department Biochemistry and Molecular Biology
Lab B302A
Street address 180 E. Green Street
City Athens
State/province GA
ZIP/Postal code 30602
Country USA
 
Platforms (2)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (24)
GSM4650355 HEK293F replicate 1
GSM4650356 HEK293F replicate 2
GSM4650357 HEK293F replicate 3
Relations
BioProject PRJNA643836
SRA SRP269805

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE153738_Filtered_raw_count_matrix.txt.gz 686.4 Kb (ftp)(http) TXT
GSE153738_Full_raw_count_matrix.txt.gz 820.1 Kb (ftp)(http) TXT
GSE153738_Normed_count_matrix_DESeq2.txt.gz 2.3 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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