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| Status |
Public on Jan 16, 2023 |
| Title |
The cis-Regulatory Landscape of Cardiac Rhythm |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Genome-wide identification of gene regulatory networks for murine cardiac conduction system
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| |
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| Overall design |
Focusing on the primary pacemaker (Sino-Atrial Node(SAN)) of the heart, we used Shox2-KI-Cre mouse line to perform cellular analysis of SAN tissue. Utilizing this SAN-specific mouse model, we performed Single cell RNA sequencing (scRNA-Seq) on neonatal (P4) Shox2-Cre/+; R26 tdTomato/+ mice to guide our single-cell atlas of the SAN.
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| |
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| Contributor(s) |
Bhattacharyya S, Goetsch S, Duan J, Li B |
| Citation |
https://doi.org/10.1172/JCI153635
|
| |
| Submission date |
Jun 30, 2020 |
| Last update date |
Jan 17, 2023 |
| Contact name |
Nikhil V Munshi |
| E-mail(s) |
Nikhil.Munshi@UTSouthwestern.edu
|
| Phone |
2146484001
|
| Organization name |
UT Southwestern Medical Center
|
| Department |
Internal Medicine-Cardiology
|
| Lab |
NB10224
|
| Street address |
6000 Harry Hines Blvd.
|
| City |
Dallas |
| State/province |
TX |
| ZIP/Postal code |
75390 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (1) |
| GSM4646683 |
P4 Shox2-Cre/+; R26 tdTomato/+ mouse SAN scRNA-seq library |
|
| Relations |
| BioProject |
PRJNA643151 |
| SRA |
SRP269337 |
