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Series GSE152156 Query DataSets for GSE152156
Status Public on Jun 04, 2021
Title Role of the metabolic sensor AMP-activated protein kinase in T cell function in vivo [TCR-seq]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Other
Summary Purpose: To investigate the function of AMPK in T cells during in vivo activation.
Methods: WT (PRKAA1fl/fl) and KO (CD4-Cre PRKAA1fl/fl) T cells were transferred into Rag KO recipients to induce adoptive T cell transfer mediated colitis. Donor WT and KO spleen and mLN T cells were isolated 6 weeks after transfer and gene expression was assessed in WT vs. KO T cells and spleen vs. mLN samples.
 
Overall design Comparison of T cell receptor (TCR) clonotypes of in vivo activated WT and KO spleen and mLN T cells.
 
Contributor(s) Mayer KA, Zlabinger GJ
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Submission date Jun 09, 2020
Last update date Jun 05, 2021
Contact name Katharina A Mayer
E-mail(s) katharina.mayer@meduniwien.ac.at
Organization name Medical University of Vienna
Department Institute of Immunology
Street address Lazarettgasse 19
City Vienna
ZIP/Postal code 1090
Country Austria
 
Platforms (1)
GPL16417 Illumina MiSeq (Mus musculus)
Samples (12)
GSM4604935 WT rep1 mLN [TCR-seq]
GSM4604936 WT rep1 spleen [TCR-seq]
GSM4604937 WT rep3 mLN [TCR-seq]
This SubSeries is part of SuperSeries:
GSE152157 Role of the metabolic sensor AMP-activated protein kinase in T cell function in vivo
Relations
BioProject PRJNA639139
SRA SRP267103

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE152156_RAW.tar 6.4 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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