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Status |
Public on Nov 06, 2020 |
Title |
RNAseq of splenic dendritic cells from 1 week-old and adult Clec9a-Cre Rosa-Tomato mice |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We use bulk RNA sequencing of sorted cells to characterize the gene expression profiles of splenic TOM+ cDC2 and TOM- DC2 from 1 week-old mice as well and of TOM+ cDC2 from adult mice. We aim to reveal transcriptional differences based on ontogeny and developmental age. Sequencing results revealed that the developmental age rather than cell origin is a major determinantof the transcriptomic differences observed between young and adult cDC2.
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Overall design |
RNA sequencing of murine dendritic cell population from the spleen
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Contributor(s) |
Papaioannou NE, Schraml BU |
Citation(s) |
33469015 |
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Submission date |
Jun 01, 2020 |
Last update date |
Jan 26, 2021 |
Contact name |
Nikolaos Papaioannou |
E-mail(s) |
Nikolaos.Papaioannou@med.uni-muenchen.de
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Organization name |
Biomedical Center
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Street address |
Großhaderner Straße 9
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City |
Planegg-Martinsried |
ZIP/Postal code |
82152 |
Country |
Germany |
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Platforms (1) |
GPL18480 |
Illumina HiSeq 1500 (Mus musculus) |
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Samples (9)
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This SubSeries is part of SuperSeries: |
GSE151595 |
Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice |
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Relations |
BioProject |
PRJNA636499 |
SRA |
SRP265525 |