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Series GSE151102 Query DataSets for GSE151102
Status Public on Jun 15, 2021
Title Disruption of Y chromosome expression in male lung cancer: replication
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Lung cancer is the single most frequent cause of cancer death worldwide and is relatively more common in males. For reasons that are currently unknown, lung cancer is also associated with significantly worse outcomes in men than women. Here we replicate clustering of Y-chromosome transcripts identified previously as showing tumor-specific disruption in men with lung cancer.
Overall design Human whole transcriptome data were generated from pulmonary tumor and, where possible, matched unaffected tissue (referred to hereon as ‘normal’) using the Affymetrix HuGene 1.1 ST microarray, giving a total of 123 samples from 69 patients. Tumor samples and adjacent normal lung tissue were donated from surgical resections, undertaken with curative intent.
Contributor(s) Arseneault M, Cookson WC, Domingo Sabugo C, Freidin MB, Kiong Lu S, Lathrop M, Liang L, Lim E, Moffatt MF, Nicholson AG, Popat S, Riazalhosseini Y, Starren E, Willis-Owen SA, Zhang Y
Citation(s) 34127738
Submission date May 23, 2020
Last update date Nov 16, 2021
Contact name William Cookson
Organization name Imperial College London
Street address Dovehouse Street
City London
ZIP/Postal code SW3 6LY
Country United Kingdom
Platforms (1)
GPL11532 [HuGene-1_1-st] Affymetrix Human Gene 1.1 ST Array [transcript (gene) version]
Samples (123)
GSM4566567 Sample n1016 (Lung, Male), Tumor
GSM4566568 Sample n1017 (Lung, Male), Tumor
GSM4566569 Sample n1019 (Lung, Male), Tumor
This SubSeries is part of SuperSeries:
GSE151103 Disruption of Y chromosome expression in male lung cancer
BioProject PRJNA634684

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE151102_RAW.tar 557.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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