|
| Status |
Public on Sep 08, 2020 |
| Title |
Memory-like HCV-specific CD8+ T cells retain a chronic scar after cure of chronic HCV infection |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Investigation of phenotypical changes between exhausted HCV-specific CD8+ T cells during chronic infection and after DAA-mediated cure investigation of heterogeneity withhin the HCV-specific CD8+ T cell population
|
| |
|
| Overall design |
Single-cell RNA sequencing of HCV-specific CD8+ T cell subsets of 6 chronically infected patients during chronic HCV infection (n=6) and after DAA-mediated HCV cure targeting conserved (n=2).
|
| |
|
| Contributor(s) |
Hensel N, Sagar -, Gruen D, Hofmann M, Thimme R |
| Citation(s) |
33398179 |
| Submission date |
May 11, 2020 |
| Last update date |
Jan 15, 2021 |
| Contact name |
Sagar - |
| E-mail(s) |
sagar@uniklinik-freiburg.de
|
| Organization name |
University Medical Center Freiburg
|
| Department |
Department of Internal Medicine II
|
| Lab |
Sagar
|
| Street address |
Hugstetter Straße 55
|
| City |
Freiburg |
| ZIP/Postal code |
79106 |
| Country |
Germany |
| |
|
| Platforms (2) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
|
| Samples (26)
|
|
| Relations |
| BioProject |
PRJNA631746 |
| SRA |
SRP261133 |
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