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Status |
Public on May 07, 2023 |
Title |
Genome-wide gene expression analysis in RAS-mutated cells with EZH2 inactivation |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
EZH2 was inactivated by shRNA in the RAS-mutated HL-60 acute myeloid leukemia cell line. RNA-seq genome wide expression profiling was used to screen for genes deregulated by EZH2 inactivation within this setting.
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Overall design |
Differential expression analysis of three EZH2 shRNA knock-out cell lines and three scrambled control shRNA cell lines in a HL-60 background.
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Contributor(s) |
Zebisch A |
Citation(s) |
33589750 |
Submission date |
May 07, 2020 |
Last update date |
Sep 18, 2023 |
Contact name |
Armin Zebisch |
E-mail(s) |
armin.zebisch@medunigraz.at
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Organization name |
Medical University of Graz
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Department |
Division of Hematology
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Street address |
Auenbruggerplatz 38
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City |
Graz |
State/province |
Styria |
ZIP/Postal code |
8036 |
Country |
Austria |
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Platforms (1) |
GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
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Samples (6)
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Relations |
BioProject |
PRJNA630966 |
SRA |
SRP260421 |