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Series GSE14960 Query DataSets for GSE14960
Status Public on Apr 16, 2009
Title Affymetrix SNP array data for low-grade astrocytoma samples
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
SNP genotyping by SNP array
Summary Copy number analysis of 21 paediatric low-grade astrocytomas identified a discrete copy number gain of 1.9Mb in chromosome band 7q34. The gain was present in 12/14 cerebellar pilocytic astrocytomas. Subsequent analysis of tumour cDNA indentified a novel gene fusion between KIAA1549 and BRAF in these tumours.
Overall design Copy number analysis of 21 paediatric low-grade astrocytomas using the Affymetrix GeneChip Human Mapping 250K Nsp Array. This study comprised 14 pilocytic astrocytomas, 4 diffuse astrocytomas, one pilomyxoid astrocytoma, one pilomyxoid glioma and one pleomorphic xanthoastrocytoma. Tumours were compared to the mean of two normal male DNA controls.
Contributor(s) Forshew T, Tatevossian RG, Lawson AR, Chaplin T, Young BD, Ellison DW, Sheer D
Citation(s) 19373855
Submission date Feb 23, 2009
Last update date May 17, 2017
Contact name Tim Forshew
Phone 02078822597
Organization name Queen Mary's School of Medicine and Dentistry
Department Centre for Neuroscience
Street address 4 Newark Street
City London
ZIP/Postal code E1 2AT
Country United Kingdom
Platforms (1)
GPL3718 [Mapping250K_Nsp] Affymetrix Mapping 250K Nsp SNP Array
Samples (23)
GSM373538 diffuse astrocytoma 2
BioProject PRJNA111833

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE14960_RAW.tar 579.0 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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