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| Status |
Public on Nov 30, 2021 |
| Title |
Effects of fetal sex on maternal immune activation (MIA)-induced transcriptional responses at the placenta |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Pregnant dams at embryonic day 11.5 and 12.5 were injected i.p. with saline or polyI:C to induce activation of the maternal immune response. Placentas from each embryo were harvested at several time points relative to the E12.5 injection over the course of gestation to evaluate the placental transcriptome after MIA.
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| Overall design |
NextGen RNA sequencing of total RNA isolated from bulk placental tissue homogenate by phenol/chloroform extraction. Sequencing performed at UVa Genome Analysis & Technology Core,
Office of Research Core Administration.
University of Virginia Health System,
P.O. Box 800741,
Charlottesville, VA 22908-0741
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| |
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| Contributor(s) |
Frost E, Lukens J, Johanson DM, Wall M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 25, 2020 |
| Last update date |
Dec 01, 2021 |
| Contact name |
David Michael Johanson |
| E-mail(s) |
dmj6ab@virginia.edu
|
| Phone |
3307327182
|
| Organization name |
UVa School of Medicine
|
| Department |
Department of Neuroscience
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| Lab |
UVa Neuroscience Bioinformatics
|
| Street address |
200 Jeanette Lancaster Way
|
| City |
Charlottesville |
| State/province |
VA |
| ZIP/Postal code |
22903 |
| Country |
USA |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (96)
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| Relations |
| BioProject |
PRJNA628095 |
| SRA |
SRP258519 |
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