|
| Status |
Public on Apr 24, 2020 |
| Title |
Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We report on gene expression, chromatin accessibility, active histone marks distribution, and Tead DNA-binding in proliferating and postmitotic organ of Corti progenitor cells.
|
| |
|
| Overall design |
Examination of gene expression (RNA-seq), chromatin accessibility (ATAC), histone modifications (CUT&RUN), and Tead-binding (CUT&RUN) in 2 cell types.
|
| |
|
| Contributor(s) |
Gnedeva K, Segil N |
| Citation(s) |
32482884 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R21 DC016984 |
Role of the Hippo-Yap signaling pathway in organ of Corti |
UNIVERSITY OF SOUTHERN CALIFORNIA |
Ksenia Gnedeva |
|
| |
| Submission date |
Apr 23, 2020 |
| Last update date |
Jun 04, 2020 |
| Contact name |
Neil Segil |
| E-mail(s) |
nsegil@med.usc.edu
|
| Phone |
3234421549
|
| Organization name |
University of Southern California
|
| Department |
BCC
|
| Lab |
503K
|
| Street address |
1425 san pablo st, BCC 503K
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90033 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (16)
|
|
| Relations |
| BioProject |
PRJNA627734 |
| SRA |
SRP258179 |
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