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Series GSE14795 Query DataSets for GSE14795
Status Public on May 26, 2010
Title Altered modulation of WNT-β-catenin and PI3K/Akt pathways in IgA nephropathy
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To uncover new molecular mechanisms involved in IgAN pathogenesis, we compared the genomic profiles of 12 IgAN patients with 8 healthy subjects,
We included addiotional disease controls 3 FSGS(Focal Segmenal glomerulosclerosis) patients and 3 membrano proliferative glomerulonephritis type I (MPGN-I) controls in our study to evaluate if the WNT-β-catenin and PI3K/Akt pathways were specfic to IgAN.
Overall design Gene expression profile comparison between 12IgAN patients and 8 Healthy Subjects. Gene Set Enrichment Analysis (GSEA) performed on the additional disease controls determined that the a priori defined set of genes and the pathways generated were specific to the IgAN
Contributor(s) Cox SN, Sallustio F, Serino G, Verrienti R, Pontrelli P, Schena FP, Zaza G, Pesce F
Citation(s) 20485333
Submission date Feb 11, 2009
Last update date Dec 06, 2018
Contact name Sharon Natasha Cox
Organization name Schena Foundation
Department Renal Lab
Street address Strada Provinciale Valenzano-Casamassima-Km3
City Valenzano-Bari
ZIP/Postal code 70010
Country Italy
Platforms (2)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (26)
GSM369302 Healthy Subject NORM1
GSM369303 Healthy Subject NORM2
GSM369304 Healthy Subject NORM3
BioProject PRJNA112079

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE14795_RAW.tar 99.7 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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