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Series GSE147633 Query DataSets for GSE147633
Status Public on Sep 28, 2022
Title Transcription regulation of SNCA by dystonia type 6 gene product THAP1 [RNA-Seq]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The predominantly function of THAP1 has been defined as a transcription factor, but how it regulates gene expression in human neurons is not well understood. Here, we found that THAP1 is able to regulate the expression of alpha-synuclein (SNCA), a key protein in Parkinson’s disease (PD).
Overall design RNA-seq analysis of THAP1 iPSC differentiated into mDA neurons
Contributor(s) Cheng F, Riess O
Citation(s) 35015830
Submission date Mar 27, 2020
Last update date Sep 29, 2022
Contact name Fubo Cheng
Organization name University of Tuebingen
Department Institute of Medical Genetics and Applied Genomics
Street address Calwerstrasse 7
City Tuebingen
ZIP/Postal code 72076
Country Germany
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (12)
GSM4437017 Control iPSCs C1-1
GSM4437018 Control iPSCs C1-2
GSM4437019 Control iPSCs C1-3
This SubSeries is part of SuperSeries:
GSE141278 Transcription regulation of SNCA by dystonia type 6 gene product THAP1
BioProject PRJNA615853
SRA SRP254312

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE147633_RAW.tar 14.3 Mb (http)(custom) TAR (of TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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