Expression profiling by high throughput sequencing
Summary
VCaP prostate cancer xenografts grown in castrated mice were treated with antiandrogen (enzalutamide), and samples were obtained during treatment response (Enza I: 5 days after initiation of the treatment) and after the treatment resistance had occurred (Enza II: 47 days after initiation of the treatment).
Overall design
Rna-seq analysis of Enza I (n = 10) and Enza II (n=10) tumor samples