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Series GSE146769 Query DataSets for GSE146769
Status Public on Apr 29, 2020
Title KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We observed changes in protein levels of EZH2, TRIM24, p53, and a substantial number of KRAB-ZF proteins in MCF7 cells upon introducing a peptide fragment containing the KRAB domain.
Overall design mRNA profiles of MCF7 cells expressing Krab domain, knockdown of TRIM28, and Vector alone, sh scrambled control were generated using deep sequencing, in duplicate
Contributor(s) Kumar J, Kaur G, Ren R, Lu Y, Lin K, Li J, Huang Y, Patel A, Barton MC, Macfarlan T, Zhang X, Cheng X
Citation(s) 32743551
Submission date Mar 11, 2020
Last update date Aug 07, 2020
Contact name Janani Kumar
Organization name MD Anderson Cancer Center
Street address 1515 Holcombe Blvd
City Houston
State/province TX
ZIP/Postal code 77030
Country USA
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (10)
GSM4405594 control_1
GSM4405595 control_2
GSM4405596 2K_1
BioProject PRJNA611924
SRA SRP252344

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE146769_RAW.tar 2.4 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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