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Series GSE14644 Query DataSets for GSE14644
Status Public on Aug 10, 2009
Title IL-4-primed bone marrow macrophages isolated from C57Bl6/J or Balb/cAnNCrl mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary To compare the expression profile of differentiated mouse bone marrow macrophages (BMM) in response to IL-4, we have employed whole genome microarray expression profiling. For this purpose, bone marrow cells were isolated from 8 to 12 weeks old C57BL6/J and Balb/cAnNCrl mice and cultured in the presence of the macrophage colony-stimulating factor (M-CSF). After seven days of culture, IL-4 was added for 4 and 18 hours.

Keywords: Mice strain comparison; Gene expression profiling
Overall design IL-4 induced gene expression was investigated in mouse bone marrow macrophages (BMM) of C57BL6/J and Balb/cAnNCrl mice. Differentiated BMM were incubated with mouse recombinant IL-4 for 4 or 18 hours or without for 18 hours. Two independent experiments were performed at each time (mock, 4 and 18 hours) using different mice littermates for each experiment.
Contributor(s) El Chartouni C, Rehli M
Citation(s) 19687144
Submission date Jan 29, 2009
Last update date Jan 12, 2017
Contact name Carol El Chartouni
Organization name University Hospital Regensburg
Department Hematology and oncology
Lab PD.Dr. Rehli
Street address Franz-Josef-Strauß Allee 11
City Regensburg
ZIP/Postal code 93053
Country Germany
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (12)
GSM365545 Balbc Mock rep 1
GSM365546 Balbc IL4 4h rep 1
GSM365547 Balbc IL4 18h rep 1
BioProject PRJNA112305

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE14644_RAW.tar 94.7 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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