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Series GSE146058 Query DataSets for GSE146058
Status Public on Jan 26, 2021
Title Pax3 plays a role in Neuro-2a cells proliferation and neurite outgrowth
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Our fingdings suggested that Pax3 not only inhibited the cell viability and proliferation, but also affected the cell cycle and the neurite outgrowth of Neuro-2a cells.RNA sequencing analysis showed upregulated genes in Pax3 overexpressed group were involved in cell cycle machinery, which may reveal the potential mechanism of proliferation.
 
Overall design We use Pax3 overexpression adenoviral to infect Neuro-2a cells. to detect the function of proliferation,cell cycle and neurite outgrowth.We use Transcriptome sequencing to detect the expression level of mRNA in infected Neuro-2a cells.
 
Contributor(s) Zhang W, Huo B
Citation(s) 33336498
Submission date Feb 27, 2020
Last update date Jan 26, 2021
Contact name Huo Bingqing
E-mail(s) huobq1993@126.com
Phone 18927483614
Organization name Shenzhen PKU-HKUST Medical Center
Street address Lianhua Road
City Shenzhen
State/province Guangdong
ZIP/Postal code 518036
Country China
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (4)
GSM4363849 NC_1
GSM4363850 NC_2
GSM4363851 Pax3_1
Relations
BioProject PRJNA609163
SRA SRP251095

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Supplementary file Size Download File type/resource
GSE146058_mRNA.expression.xls.gz 914.3 Kb (ftp)(http) XLS
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Raw data are available in SRA
Processed data are available on Series record

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