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Series GSE14490 Query DataSets for GSE14490
Status Public on Jan 22, 2009
Title Transcriptome modulation analysis of cytomegalovirus-infected immature monocyte-derived dendritic cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Analysis of dendritic cells (DCs) at 6h and 48h after infection with cytomegalovirus (CMV) versus non infected. CMV tends to induce immunosuppression followed by lasting immunity. DCs appear to play a role in this effect. Results provide insights into CMV/DC interactions and suggest mechanisms for CMV-regulated early immune response.

Keywords: gene expression array-based, count
 
Overall design In the present study, immature monocyte-derived dendritic cells were generated from CMV neg healthy blood donors and infected or not with an endotheliotropic CMV strain. Gene expression modulation by the CMV infection was studied in a time course assay (non-infected - NI - vs 6h or 48h post-infection. Patient C has no 48h sample
 
Contributor(s) Haspot F, Bihouée A, Chevalier C, Houlgatte R, Halary F
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jan 21, 2009
Last update date Feb 22, 2018
Contact name Franck Halary
E-mail(s) franck.halary@univ-nantes.fr
Phone (33)240087412
Organization name INSERM UMR643
Department ITERT - CHU Hotel Dieu
Street address 30, bd Jean Monnet
City Nantes
ZIP/Postal code 44093
Country France
 
Platforms (1)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (20)
GSM361934 Patient A non infected
GSM361935 Patient B non infected
GSM361936 Patient C non infected
Relations
BioProject PRJNA111545

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE14490_RAW.tar 161.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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