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Series GSE144698 Query DataSets for GSE144698
Status Public on Jun 05, 2021
Title tRF-seq landscapes the variation of tRNA derived fragments after mouse liver injury
Organism Mus musculus
Experiment type Other
Summary In order to intensively elucidate the metabolic characteristics of tRFs after liver injury, we performed tRF-seq by high throughput sequencing. We found that after liver injury, large abundance of tRFs were produced. Especially, the tRF-1s largely vary during the liver injury process and may play important role in the liver disease.
 
Overall design WT and NS-KO mice were once or repeated injected CCl4, recorded as Day 3 or Day 27. The control mice of WT or NS-KO were injected corn oil, recorded as Day 0. The mice livers were collected and used for tRF-seq, in duplicate, using Illumina NextSeq 500 system.
 
Contributor(s) Ying S, Zhou Q
Citation(s) 37015921
Submission date Feb 03, 2020
Last update date May 02, 2023
Contact name Sunyang YING
E-mail(s) yingsunyang@ioz.ac.cn
Phone 13021027424
Organization name Chinese Academy of Sciences
Department State key laboratory of stem cell and reproductive biology
Lab Zhou
Street address 1-5 Beichen West Road, Chaoyang District, Beijing
City Beijing
State/province Beijing
ZIP/Postal code 100101
Country China
 
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (12)
GSM4293943 WT D0 rep1
GSM4293944 WT D0 rep2
GSM4293945 WT D3 rep1
Relations
BioProject PRJNA604603
SRA SRP246935

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE144698_Alignment_to_tRNAs.txt.gz 1.5 Mb (ftp)(http) TXT
GSE144698_All_Differentially_Expressed_tRF.xlsx 904.6 Kb (ftp)(http) XLSX
GSE144698_Differentially_Expressed_tRF.xlsx 197.0 Kb (ftp)(http) XLSX
GSE144698_Expression_tRF.xlsx 172.0 Kb (ftp)(http) XLSX
GSE144698_Normalized_CPM_All_Differentially_Expressed_tRF.xlsx 904.5 Kb (ftp)(http) XLSX
GSE144698_Normalized_CPM_Differentially_Expressed_tRF.xlsx 197.0 Kb (ftp)(http) XLSX
GSE144698_RAW.tar 36.7 Mb (http)(custom) TAR (of FA, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record
Processed data provided as supplementary file

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