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Status |
Public on Jun 05, 2021 |
Title |
tRF-seq landscapes the variation of tRNA derived fragments after mouse liver injury |
Organism |
Mus musculus |
Experiment type |
Other
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Summary |
In order to intensively elucidate the metabolic characteristics of tRFs after liver injury, we performed tRF-seq by high throughput sequencing. We found that after liver injury, large abundance of tRFs were produced. Especially, the tRF-1s largely vary during the liver injury process and may play important role in the liver disease.
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Overall design |
WT and NS-KO mice were once or repeated injected CCl4, recorded as Day 3 or Day 27. The control mice of WT or NS-KO were injected corn oil, recorded as Day 0. The mice livers were collected and used for tRF-seq, in duplicate, using Illumina NextSeq 500 system.
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Contributor(s) |
Ying S, Zhou Q |
Citation(s) |
37015921 |
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Submission date |
Feb 03, 2020 |
Last update date |
May 02, 2023 |
Contact name |
Sunyang YING |
E-mail(s) |
yingsunyang@ioz.ac.cn
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Phone |
13021027424
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Organization name |
Chinese Academy of Sciences
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Department |
State key laboratory of stem cell and reproductive biology
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Lab |
Zhou
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Street address |
1-5 Beichen West Road, Chaoyang District, Beijing
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City |
Beijing |
State/province |
Beijing |
ZIP/Postal code |
100101 |
Country |
China |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (12)
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Relations |
BioProject |
PRJNA604603 |
SRA |
SRP246935 |