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Series GSE144499 Query DataSets for GSE144499
Status Public on Sep 21, 2020
Title miR-199 Family Regulates Sonic Hedgehog Expression During Craniofacial Development
Platform organisms Caenorhabditis elegans; Drosophila melanogaster; Danio rerio; Gallus gallus; Homo sapiens; Mus musculus; Rattus norvegicus
Sample organism Gallus gallus
Experiment type Expression profiling by array
Summary Through microarray analyses of three SHH conditions, we were able to identify the miR-199 family as a family of miRNAs that is regulated by SHH signaling from the brain.
 
Overall design To identify miRNAs that are regulated by SHH signaling within the brain and are active during the development of the upper jaw, we performed miRNA microarray analysis on the chick frontonasal ectodermal zone in normal embryos before (HH18) and after (HH22) the onset of SHH expression, after activating SHH (SHH-N or PBS control) or blocking SHH (5E1 or 40-1A control) signaling in the neural tube at HH10 and examined gene expression at HH22.
 
Contributor(s) Hu D, Marcucio R
Citation(s) 32391617
Submission date Jan 29, 2020
Last update date Sep 21, 2020
Contact name Andrea J Barczak
Organization name UCSF Sandler Center Functional Genomics Core Facility
Street address 1550 4th St Rock Hall 545
City San Francisco
State/province CA
ZIP/Postal code 94143
Country USA
 
Platforms (1)
GPL28095 Agilent-021542 miRNA-v3.2-8x15K array [Feature Number]
Samples (24)
GSM4289675 Ectoderm sample 1 from chick treated with 5E1
GSM4289676 Ectoderm sample 2 from chick treated with 5E1
GSM4289677 Ectoderm sample 3 from chick treated with 5E1
Relations
BioProject PRJNA603793

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE144499_RAW.tar 44.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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