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| Status |
Public on Jun 29, 2022 |
| Title |
Consticted migration is associated with stable 3D genome structure differences in cancer cells (Hi-C) |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
We investigated the effect of constricted migration (using transwell assays with 5-μm or 12-μm in diameter) on the organization of the 3D genome in melanoma and breast cancer cells.
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| Overall design |
Hi-C was performed to investigate changes in 3D genome organization after constricted migration. This experiment was performed on all sub-populations of A375 with two biological replicates per condition.
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| Contributor(s) |
Golloshi R, Playter C, Freeman TF, Das P, Raines TI, Garretson JH, Thurston D, McCord RP |
| Citation missing |
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| Submission date |
Jan 14, 2020 |
| Last update date |
Nov 29, 2022 |
| Contact name |
Rosela Golloshi |
| E-mail(s) |
rgollosh@vols.utk.edu
|
| Organization name |
University of Tennessee Knoxville
|
| Department |
Department of Biochemistry & Cellular and Molecular Biology
|
| Lab |
Rachel Patton McCord Lab
|
| Street address |
1311 Cumberland Avenue
|
| City |
Knoxville |
| State/province |
TN |
| ZIP/Postal code |
37996 |
| Country |
USA |
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| Platforms (2) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (27)
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| This SubSeries is part of SuperSeries: |
| GSE143678 |
Consticted migration is associated with stable 3D genome structure differences in cancer cells |
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| Relations |
| BioProject |
PRJNA601219 |
| SRA |
SRP241953 |
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