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| Status |
Public on Mar 03, 2009 |
| Title |
Expression data from adipocytes and white adipose tissue of mice maintained on normal chow or high fat diet |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
We studied the role of the cAMP responsive factor CREB in promoting insulin resistance following its activation in adipose under obese conditions
We identified genes that were upregulated in primary cultures of mouse adipocytes following exposure to forskolin; and we characterized genes that are also induced in white adipose tissue in mice maintained on a high fat diet.
Keywords: signaling study
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| Overall design |
Primary cultures of mouse adipocytes,harvested from visceral adipose tissue, were exposed to forskolin (10uM) or vehicle control (DMSO) for 2 hours. White adipose tissue (epididymal fat pads) were collected from mice maintained on a 60% high fat diet for 12 weeks and from control mice on normal chow.
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| Contributor(s) |
Montminy M, Qi L |
| Citation(s) |
19254572 |
| |
| Submission date |
Jan 09, 2009 |
| Last update date |
May 04, 2018 |
| Contact name |
Marc Montminy |
| E-mail(s) |
montminy@salk.edu
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| Organization name |
The Salk Institute
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| Street address |
10010 N. Torrey Pines Rd.
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| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
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| Platforms (1) |
| GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA111399 |
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