|
| Status |
Public on Dec 16, 2020 |
| Title |
CRISPRi screen of prostate cancer associated risk cis-regulatory elements [Hi-C] |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
Prostate cancer (PCa) associated risk SNPs are enriched in cis-regulatory elements (CREs). In this study, we screened 260 CREs that contain at least one PCa risk SNP for essentiality in V16A, 22Rv1 and A549 cells. We tiled the CREs and 14 control regions using 5,873 sgRNAs.
|
| |
|
| Overall design |
Hi-C in V16A and 22Rv1 cells.
|
| |
|
| Contributor(s) |
He HH |
| Citation(s) |
33741908 |
| |
| Submission date |
Jan 09, 2020 |
| Last update date |
Apr 20, 2021 |
| Contact name |
Musaddeque Ahmed |
| E-mail(s) |
musaddeque.ahmed@gmail.com
|
| Organization name |
University health Network
|
| Lab |
He Lab
|
| Street address |
101 College St
|
| City |
Toronto |
| State/province |
ON |
| ZIP/Postal code |
M5G1L7 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (4)
|
|
| This SubSeries is part of SuperSeries: |
| GSE142811 |
CRISPRi screen of prostate cancer associated risk cis-regulatory elements |
|
| Relations |
| BioProject |
PRJNA600239 |
| SRA |
SRP240924 |
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