GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE142871 Query DataSets for GSE142871
Status Public on Jun 03, 2020
Title PIM kinase inhibition in HCC xenograft
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Human HCC cell line, MHCC-97L, was subcutaneously injected to BALB/c nude mice. Two weeks post injection, mice were randomised to receive vehicle or PIM447 (60mg/kg) by oral gavage three times a week for two weeks. Total RNA was extracted from the tumor xenograft (Vehicle, n=2; PIM447, n=2) and subjected to RNA sequencing. Expression profiling of the tumors between vehicle control and PIM447 treated groups was compared.
Overall design Total RNA extracted from tumor xenograft of mice treated with vehicle (n=2) and PIM447 (n=2) were subjected to RNA sequencing profiling.
Contributor(s) Lo R
Citation(s) 32558942
Submission date Jan 02, 2020
Last update date Jun 21, 2020
Contact name Chi Ho Lin
Phone +852 2831 5511
Organization name The University of Hong Kong
Department Centre for PanorOmic Sciences
Street address 6th Floor, The Hong Kong Jockey Club Building for Interdisciplinary Research, 5 Sassoon Road, Pokfulam
City Hong Kong
ZIP/Postal code Hong Kong
Country Hong Kong
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (4)
GSM4246843 Ctrl1
GSM4246844 Ctrl5
GSM4246845 PIM7
BioProject PRJNA598723
SRA SRP239327

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE142871_RAW.tar 1.2 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap