|
| Status |
Public on Jun 03, 2020 |
| Title |
PIM kinase inhibition in HCC xenograft |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Human HCC cell line, MHCC-97L, was subcutaneously injected to BALB/c nude mice. Two weeks post injection, mice were randomised to receive vehicle or PIM447 (60mg/kg) by oral gavage three times a week for two weeks. Total RNA was extracted from the tumor xenograft (Vehicle, n=2; PIM447, n=2) and subjected to RNA sequencing. Expression profiling of the tumors between vehicle control and PIM447 treated groups was compared.
|
| |
|
| Overall design |
Total RNA extracted from tumor xenograft of mice treated with vehicle (n=2) and PIM447 (n=2) were subjected to RNA sequencing profiling.
|
| |
|
| Contributor(s) |
Lo R |
| Citation(s) |
32558942 |
| Submission date |
Jan 02, 2020 |
| Last update date |
Jun 21, 2020 |
| Contact name |
Chi Ho Lin |
| E-mail(s) |
nicklin.cpos@hku.hk
|
| Phone |
+852 2831 5511
|
| Organization name |
The University of Hong Kong
|
| Department |
Centre for PanorOmic Sciences
|
| Street address |
6th Floor, The Hong Kong Jockey Club Building for Interdisciplinary Research, 5 Sassoon Road, Pokfulam
|
| City |
Hong Kong |
| ZIP/Postal code |
Hong Kong |
| Country |
Hong Kong |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA598723 |
| SRA |
SRP239327 |
Less...
More...