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Series GSE142695 Query DataSets for GSE142695
Status Public on Feb 26, 2020
Title Analysis of gene expression in lung adenocarcinoma cells following over-expression of miR-30a-5p or miR-30a-3p
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RNA-sequencing was performed to gain insight into the transcriptome-wide molecular changes induced by miR-30a-5p or miR-30a-3p over-expression in lung adenocarcinoma cells. Following transfection of miR-30a-5p or miR-30a-3p miRNA mimic or control RNA, RNA-sequencing was performed. This high-throughput data revealed elevated expression of both miR-30a-5p and miR-30a-3p reduced the expression of genes and pathways known to induce proliferation and movement in lung adenocarcinoma cells.
Overall design miR-30a-5p or miR-30a-3p was transfected in lung adenocarcinoma cells and gene expression profiles were generated using RNA-sequencing.
Contributor(s) Eischen CM, Mitra R
Citation(s) 32080184
Submission date Dec 28, 2019
Last update date Aug 17, 2022
Contact name Ramkrishna Mitra
Organization name Thomas Jefferson University
Street address 233 S 10th street
City Philadelphia
State/province Pennsylvania
ZIP/Postal code 19107
Country USA
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (9)
GSM4237848 control_rep1
GSM4237849 control_rep2
GSM4237850 control_rep3
BioProject PRJNA597999
SRA SRP238971

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE142695_RAW.tar 2.7 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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