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Series GSE141410 Query DataSets for GSE141410
Status Public on Dec 04, 2019
Title Transcriptome analysis between primary and iPS-derived monocytes and macrophages and comparison of iPS-derived macrophages between CCR5 patients and healthy controls
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary iPS-derived monocytes and macrophages are similar with primary monocytes and macrophages compared to iPS cells from the genome-wide overview and have similar gene expression patterns.
Overall design Primary monocytes were isolated from peripheral blood collected from 8 healthy volunteers and differentiated to macrophages; iPS cells are reprogrammed from skin fibroblast obtained from 3 healthy controls and then differentiated to patient specific iPS-derived monocytes(imono) and macrophages(iMac)cells, and mRNA expression profiles were analyzed by RNA-Seq.
*** Submitter declares that the raw data will be deposited in dbGaP due to patient privacy concerns.
Contributor(s) Boehm M, Ping X
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Dec 03, 2019
Last update date Dec 04, 2019
Contact name Manfred Boehm
Organization name NHLBI
Street address 9000 Rockbille Pike
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (43)
GSM4202440 iPS_ctrl_3
GSM4202441 iPS_ctrl_4
GSM4202442 iPS_ctrl_6
BioProject PRJNA593302

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE141410_Mono_RNASeq.txt.gz 1.3 Mb (ftp)(http) TXT
Processed data are available on Series record
Raw data not provided for this record

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