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| Status |
Public on Dec 04, 2019 |
| Title |
Transcriptome analysis between primary and iPS-derived monocytes and macrophages and comparison of iPS-derived macrophages between CCR5 patients and healthy controls |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
iPS-derived monocytes and macrophages are similar with primary monocytes and macrophages compared to iPS cells from the genome-wide overview and have similar gene expression patterns.
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| Overall design |
Primary monocytes were isolated from peripheral blood collected from 8 healthy volunteers and differentiated to macrophages; iPS cells are reprogrammed from skin fibroblast obtained from 3 healthy controls and then differentiated to patient specific iPS-derived monocytes(imono) and macrophages(iMac)cells, and mRNA expression profiles were analyzed by RNA-Seq.
*** Submitter declares that the raw data will be deposited in dbGaP due to patient privacy concerns.
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| Contributor(s) |
Boehm M, Ping X |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Dec 03, 2019 |
| Last update date |
Dec 04, 2019 |
| Contact name |
Manfred Boehm |
| Organization name |
NHLBI
|
| Street address |
9000 Rockbille Pike
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
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| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
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| Samples (43)
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| Relations |
| BioProject |
PRJNA593302 |
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