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Series GSE141244 Query DataSets for GSE141244
Status Public on Sep 28, 2022
Title Transcription regulation of SNCA by dystonia type 6 gene product THAP1 [ChIP-seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The predominantly function of THAP1 has been defined as a transcription factor, but how it regulates gene expression in human neurons is not well understood. Here, we found that THAP1 is able to regulate the expression of alpha-synuclein (SNCA), a key protein in Parkinson’s disease (PD).
Overall design ]analysis of SNCA promoter interact regions
Contributor(s) Cheng F, Riess O
Citation(s) 35015830
Submission date Dec 02, 2019
Last update date Sep 29, 2022
Contact name Fubo Cheng
Organization name University of Tuebingen
Department Institute of Medical Genetics and Applied Genomics
Street address Calwerstrasse 7
City Tuebingen
ZIP/Postal code 72076
Country Germany
Platforms (2)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (10)
GSM4199227 anti-flag ChIP-seq THAP1
GSM4199228 anti-flag ChIP-seq empty vec
GSM4199229 CTCF ChIP-seq
This SubSeries is part of SuperSeries:
GSE141278 Transcription regulation of SNCA by dystonia type 6 gene product THAP1
BioProject PRJNA592921
SRA SRP234407

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE141244_RAW.tar 4.2 Gb (http)(custom) TAR (of BED, BIGWIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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