GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE139918 Query DataSets for GSE139918
Status Public on Dec 01, 2021
Title Next Generation Sequencing Facilitates Quantitative Analysis of CRC cells with low DUOX2 expression compared with the control group
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Purpose: The purpose of this study was to analyze changes in the cell genome along with the downregulation of DUOX2, as well as changes in gene enrichment pathways, so as to find the downstream target genes of DUOX2
Conclusions: Our study is the first detailed analysis of DUOX2's effect on the genome of CRC cells.We concluded that changes in DUOX2 gene levels can lead to activation of multiple tumor-related signaling pathways, and that NGS provides a more comprehensive and accurate method for quantitative and qualitative assessment of cell mRNA content.
Overall design CRC cells with low DUOX2 expression compared with the control group
Contributor(s) Zhang X, Wang G
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Nov 05, 2019
Last update date Dec 01, 2021
Contact name Xue Zhang
Organization name Hebei Medical University Fourth Affiliated Hospital
Department Department of Medical Oncology
Street address 12 Jiankang Road
City Shijiazhuang
State/province Hebei
ZIP/Postal code 050000
Country China
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (3)
GSM4148788 si1
GSM4148789 si2
GSM4148790 NC
BioProject PRJNA587629
SRA SRP228568

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE139918_gene_expression.txt.gz 2.6 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap